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ROUGH ENDOPLASMIC RETICULUM
Rough (granular) endoplasmic reticulum is a system of intracellular membranes looking rough because of multiple ribosome particles attached to them. A part of the rough endoplasmic reticulum is in direct contact with the
nuclear membrane. The inner cavity of the rough endoplasmic reticulum is called cisterna. On the membranes of the rough endoplasmic reticulum proteins, destined either for secretion into the intracellular medium, or for insertion into the plasma membrane, are synthesized.
The secretion of
proteins is preceded by a succession of event beginning with transfer of the protein chain having been synthesized on
ribosomes, into the inner cavity of the rough endoplasmic reticulum (cisterna). After this the protein included into special vesicles is transported into the Golgi complex, and then is extracted from there into the intracellular fluid.
Supplementary information
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